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REVIEW ARTICLE
Year : 2022  |  Volume : 1  |  Issue : 2  |  Page : 67-75

A review on anticancer potential of Berberis aristata and berberine with focus on quantitative methods


Department of Pharmaceutical Quality Assurance, PES Modern College of Pharmacy for Ladies, Pune, Maharashtra, India

Correspondence Address:
Ms. Manasi Rokade
PES Modern College of Pharmacy for Ladies, Moshi, Pune - 412 105, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jpdtsm.jpdtsm_9_22

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Berberis aristata (BA) is a traditional herbal ayurvedic medicine widely used from ancient time and has various therapeutic effect. In this review, we had tried to emphasize on its pharmacognistic as well phytochemical parameters. We had aiming to focus on estimation of berberin in extract using different analytical techniques such as high-performance liquid chromatography, high-performance thin-layer chromatography from various parts of BA plant. It contains different isoquinoline alkaloids, namely berberine, palmitine, berbamine which are contributing in the pharmacological action of BA. As it has various pharmacological actions such as anti-bacterial, anti-diarrheal, anti-inflammatory, anti-pyretic, and anti-hemorrhagic. Along with that, it is also a potential anticancer agent as its methanolic extract showed potent activity against different cell lines such as breast cancer, colon cancer, cervical cancer cell lines. In this review, we had emphasized on phamacognosy, phytochemistry, and analysis for berberine content of BA along with its anticancer potential. A brief spotlight had also given on anticancer prospective of berberine.


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